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<p>Indirect quantification of valvular regurgitation using cardiovascular magnetic resonance assumes agreement among left ventricular stroke volume (LV–SV), right ventricular stroke volume (RV–SV), and forward flow in the ascending aorta (Ao) and pulmonary artery (PA). This study evaluated agreement among these parameters in healthy subjects. In 15 healthy volunteers, LV–SV and RV–SV were calculated from LV short-axis cine images, and Ao and PA flows were measured using phase-contrast MRI. Agreement among six parameter pairs was assessed using Bland–Altman analysis and intraclass correlation coefficients (ICC). Bland–Altman analysis demonstrated negative additive bias in RV–PA, RV–Ao, and RV–LV comparisons, indicating underestimation of RV–SV. Complementary ICC analysis showed moderate agreement in all RV–related pairs. Indirect regurgitant volume estimation based on LV–Ao appears robust, whereas RV–PA may underestimate regurgitant volume when RV–SV is derived from LV short-axis cine imaging.</p>

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Agreement between ventricular stroke volumes and great vessel flow using cine and phase-contrast MRI in healthy subjects

  • 期刊论文

  • 发表日期：

    2026年6月16日

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  • Ai Kawaguchi,
  • Wataru Kawaguchi,
  • Miyuki Hayashi,
  • Kenji Yasuda,
  • Yoichi Ohashi

摘要

Indirect quantification of valvular regurgitation using cardiovascular magnetic resonance assumes agreement among left ventricular stroke volume (LV–SV), right ventricular stroke volume (RV–SV), and forward flow in the ascending aorta (Ao) and pulmonary artery (PA). This study evaluated agreement among these parameters in healthy subjects. In 15 healthy volunteers, LV–SV and RV–SV were calculated from LV short-axis cine images, and Ao and PA flows were measured using phase-contrast MRI. Agreement among six parameter pairs was assessed using Bland–Altman analysis and intraclass correlation coefficients (ICC). Bland–Altman analysis demonstrated negative additive bias in RV–PA, RV–Ao, and RV–LV comparisons, indicating underestimation of RV–SV. Complementary ICC analysis showed moderate agreement in all RV–related pairs. Indirect regurgitant volume estimation based on LV–Ao appears robust, whereas RV–PA may underestimate regurgitant volume when RV–SV is derived from LV short-axis cine imaging.