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<p>This study evaluates the clinical feasibility and surface conformity of ClearFit2-Encapsulated, a technical configuration implemented to facilitate the clinical use of highly adhesive transparent boluses through a film-dressing encapsulation method for post-mastectomy radiation therapy (PMRT). ClearFit2 was encapsulated with a thin polyurethane film. Following benchmark phantom comparisons of three bolus configurations (ClearFit1, ClearFit2, and ClearFit2-Encapsulated) using planning CT, clinical performance was evaluated in eight PMRT patients using weekly cone-beam CT (CBCT) to quantify air-gap distances. In phantom evaluation, mean gaps were 3.9 ± 3.1&#xa0;mm for ClearFit1, 0.9 ± 0.9&#xa0;mm for ClearFit2, and 2.2 ± 2.2&#xa0;mm for ClearFit2-Encapsulated. In clinical evaluation, the median air-gap distance across all cases was 1.1&#xa0;mm (range: 0.6–1.7&#xa0;mm), with 88.2% of the interface area maintaining gaps ≤ 3&#xa0;mm. ClearFit2-Encapsulated demonstrates high surface conformity and clinical feasibility, providing a practical bolus-handling solution for patients undergoing PMRT.</p>

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Encapsulated configuration of a flexible transparent adhesive bolus to improve surface conformity and skin safety in post-mastectomy radiation therapy

  • 期刊论文

  • 发表日期：

    2026年3月23日

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  • Hideharu Miura,
  • Kenji Kanemoto,
  • Toshiya Okazue,
  • Shuichi Ozawa,
  • Masahiro Kenjo

摘要

This study evaluates the clinical feasibility and surface conformity of ClearFit2-Encapsulated, a technical configuration implemented to facilitate the clinical use of highly adhesive transparent boluses through a film-dressing encapsulation method for post-mastectomy radiation therapy (PMRT). ClearFit2 was encapsulated with a thin polyurethane film. Following benchmark phantom comparisons of three bolus configurations (ClearFit1, ClearFit2, and ClearFit2-Encapsulated) using planning CT, clinical performance was evaluated in eight PMRT patients using weekly cone-beam CT (CBCT) to quantify air-gap distances. In phantom evaluation, mean gaps were 3.9 ± 3.1 mm for ClearFit1, 0.9 ± 0.9 mm for ClearFit2, and 2.2 ± 2.2 mm for ClearFit2-Encapsulated. In clinical evaluation, the median air-gap distance across all cases was 1.1 mm (range: 0.6–1.7 mm), with 88.2% of the interface area maintaining gaps ≤ 3 mm. ClearFit2-Encapsulated demonstrates high surface conformity and clinical feasibility, providing a practical bolus-handling solution for patients undergoing PMRT.