<p>This study investigates the structural architecture of Al-Madinah region in western Saudi Arabia through integrated analysis of remote sensing and aeromagnetic data. The research aims to delineate both surface and subsurface structural features and evaluate their relationship to the regional tectonic framework. Three complementary analytical techniques—Euler Deconvolution, Local Wavenumber Method, and Tilt Angle Method—were applied to aeromagnetic data, while satellite imagery was analyzed to identify surface lineaments. The results reveal a complex network of fault systems predominantly trending in Northwest-Southeast, parallel to the Red Sea, and Northeast-Southwest directions, consistent with the regional extensional tectonics. The depth of magnetic sources varies from shallow levels in the central and northeastern sectors, linked to the volcanic flows of Harrat Rahat and Harrat Khaybar, to deeper magnetic structures in the southeastern portion. This spatial differentiation provides new insights into the region’s structural complexity. The findings have significant implications for seismic hazard assessment and groundwater resource management in this geologically active region, and contribute to understanding the potential effects of recent tectonic activities in the western province of Saudi Arabia.</p>