<p>Family context plays a key role in school stress, which has a high prevalence rate among adolescents worldwide. The present study has two aims. First, to analyse, separately for boys and girls, the role of parental control (behavioural and psychological) and adolescents’ information management (secrecy-concealment, routine disclosure and self-disclosure) in school stress (linked to school performance, future uncertainty and school/leisure conflict). The second aim is to explore the potential moderating effect of parental control on the relationship between adolescents’ information management and school stress. The sample comprised 4,768 Spanish adolescents (2,482 girls and 2,286 boys) aged 11-17 years from the EASE research project. Data collection assured the anonymity and confidentiality of participants’ responses. Statistical analyses were linear regressions, performed separately for boys and girls. We found that parental control and adolescents’ information management were associated with school stress. Moreover, parental psychological control moderated the association between routine disclosure and school stress, as well as the association between secrecy-concealment and school stress. In terms of gender differences in their associations with school stress, disclosure was more important for girls, and secrecy-concealment showed the stronger contribution among boys. Findings from this study contribute to advancing our understanding of the role of families in adolescent school stress, by identifying important gender differences, while emphasising the detrimental role of psychological control and the potential benefits of a warm, non-intrusive and communicative family context for lower adolescent school stress.</p>