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<p>Advanced breast cancer represents a challenge for patients and physicians due to its dynamic genomic changes, which are associated with resistance to treatments. The main goals of treatment in advanced breast cancer are to improve patient quality of life and to increase patient survival. This is achieved using the most appropriate sequence of treatments based on knowledge of the natural history of the disease. In these guidelines (updated in 2025), we summarize current evidence and available therapies for the medical management of advanced breast cancer.</p>

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SEOM-GEICAM-SOLTI clinical guidelines in advanced breast cancer (UPDATE 2025)

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月3日

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  • Jose Angel Garcia‑Saenz,
  • Isabel Blancas Lopez-Barajas,
  • Isabel Echavarria,
  • Carmen Hinojo Gonzalez,
  • Mireia Margeli Vila,
  • Fernando Moreno Antón,
  • Sonia Pernas,
  • Teresa Ramon y Cajal,
  • Nuria Ribelles,
  • Meritxell Bellet Ezquerra

摘要

Advanced breast cancer represents a challenge for patients and physicians due to its dynamic genomic changes, which are associated with resistance to treatments. The main goals of treatment in advanced breast cancer are to improve patient quality of life and to increase patient survival. This is achieved using the most appropriate sequence of treatments based on knowledge of the natural history of the disease. In these guidelines (updated in 2025), we summarize current evidence and available therapies for the medical management of advanced breast cancer.