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<p>To assess the diagnostic utility of USG and FNAC with reference to histopathology in neck swellings. Between September 2022 and February 2024, a prospective observational study was undertaken. The study included 60 patients of both genders after written informed consent. Data sets comprised ultrasonography, FNAC, and histopathology findings. Prevalence rates with 95% confidence intervals were determined. Pearson’s chi-square test compared categorical data, while correlations between numeric outcomes were assessed using Karl Pearson’s or Spearman’s coefficients. Significance was set at <i>P</i> &lt; 0.05; results above this threshold were regarded as non-significant. This study assessed 60 patients with neck swellings, comparing ultrasound (USG) and fine needle aspiration cytology (FNAC) findings against histopathological diagnosis. Among thyroid swellings, colloid goiter was the most prevalent (28%), followed by follicular adenoma (13.3%), multinodular goiter (6.7%), and adenomatous goiter (5.3%). Non-thyroid lesions included lipoma as the most common, with sialadenitis, thyroglossal cyst, ranula, and pleomorphic adenoma also identified. FNAC demonstrated superior diagnostic performance metrics—sensitivity, specificity, positive and negative predictive values, and accuracy—compared to USG for thyroid swellings such as colloid goiter, follicular adenoma, adenomatous goiter, and multinodular goiter. In non-thyroid lesions, both FNAC and USG demonstrated similar accuracy in diagnosing lipoma, sialadenitis, thyroglossal cyst, and pleomorphic adenoma. Specifically, FNAC achieved perfect accuracy (100%) in diagnosing sialadenitis and pleomorphic adenoma, slightly higher than the 98.7% accuracy by USG. FNAC is a more accurate diagnostic tool than USG for thyroid swellings, while both techniques perform comparably in non-thyroid neck swellings.</p>

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Diagnostic Findings of USG and FNAC with Reference to Histopathology in Neck Swellings in Tertiary Care Center

  • 期刊论文

  • 发表日期：

    2026年3月30日

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  • Mansi Kaveeshwar,
  • Praveen Surana,
  • Brajendra Baser,
  • Arvind Kumar Gupta

摘要

To assess the diagnostic utility of USG and FNAC with reference to histopathology in neck swellings. Between September 2022 and February 2024, a prospective observational study was undertaken. The study included 60 patients of both genders after written informed consent. Data sets comprised ultrasonography, FNAC, and histopathology findings. Prevalence rates with 95% confidence intervals were determined. Pearson’s chi-square test compared categorical data, while correlations between numeric outcomes were assessed using Karl Pearson’s or Spearman’s coefficients. Significance was set at P < 0.05; results above this threshold were regarded as non-significant. This study assessed 60 patients with neck swellings, comparing ultrasound (USG) and fine needle aspiration cytology (FNAC) findings against histopathological diagnosis. Among thyroid swellings, colloid goiter was the most prevalent (28%), followed by follicular adenoma (13.3%), multinodular goiter (6.7%), and adenomatous goiter (5.3%). Non-thyroid lesions included lipoma as the most common, with sialadenitis, thyroglossal cyst, ranula, and pleomorphic adenoma also identified. FNAC demonstrated superior diagnostic performance metrics—sensitivity, specificity, positive and negative predictive values, and accuracy—compared to USG for thyroid swellings such as colloid goiter, follicular adenoma, adenomatous goiter, and multinodular goiter. In non-thyroid lesions, both FNAC and USG demonstrated similar accuracy in diagnosing lipoma, sialadenitis, thyroglossal cyst, and pleomorphic adenoma. Specifically, FNAC achieved perfect accuracy (100%) in diagnosing sialadenitis and pleomorphic adenoma, slightly higher than the 98.7% accuracy by USG. FNAC is a more accurate diagnostic tool than USG for thyroid swellings, while both techniques perform comparably in non-thyroid neck swellings.