Scholarlink

Introduction <p>A solitary mass that may be sessile or pedunculated is the hallmark of a peripheral ossifying fibroma. The lesion typically measures less than 1.5&#xa0;cm in diameter, but in rare cases, it may enlarge to sizes ranging from 6 to 9&#xa0;cm. It is usually considered as a reactive lesion, with its origin believed to be from the periodontal ligament. This study aims to identify the factors contributing to the recurrence of Ossifying Fibroma, as well as those associated with favourable outcomes and the prevention of recurrence. This study underscores the importance of thorough surgical management and vigilant post-operative care in improving the prognosis of POF and minimizing the risk of recurrence.</p> Method <p>A retrospective view was done from Institute’s medical record department from January 2019 to December 2024. The following data was obtained from the lesion; age at presentation, gender, site and size of the lesion, radiographic presentation (locularity), presence of irritants and local inflammatory factors, systemic health of the patient and post-op care. Patients were monitored regularly and followed for 5 years to assess for potential recurrence of the lesion.</p> Result <p>This retrospective observational cohort study evaluated 43 patients clinically and radiographically diagnosed with ossifying fibroma, with a mean age of 38.88 years and a female predominance (67.4%). Mandibular (62.8%) and posterior jaw (62.8%) involvement were most frequent. Radiographically, unilocular (55.8%) and mixed radiolucent-radiopaque (62.8%) patterns were more common. Recurrence was observed in 18.6% of cases. A significant correlation was noted between gender and confounding factors (<i>p</i> = 0.038). Lesion size averaged 6.62&#xa0;cm, with larger lesions potentially linked to higher recurrence risk.</p> Conclusion <p>Ossifying fibroma demonstrates a predilection for females in the third to fifth decades of life, with a marked tendency for mandibular and posterior jaw involvement. Radiographically, the majority of lesions exhibited a unilocular architecture with a characteristic mixed radiolucent-radiopaque pattern. Recurrence was documented in 18.6% of cases; however, no statistically significant associations were found with site, radiographic features, or systemic health. A noteworthy correlation was identified between gender and the presence of confounding factors, potentially indicating an increased susceptibility to lesion recurrence in affected patients. These findings underscore the importance of vigilant clinical and radiographic surveillance to effectively monitor and manage the potential for recurrence in ossifying fibroma cases.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Unravelling the Predictive Factors of Recurrence and Survival Without Recurrence in Ossifying Fibroma

  • 期刊论文

  • 发表日期：

    2026年3月17日

查看全文
  • Sapna Tandon,
  • Himanshu Chauhan,
  • Hemant Mehra,
  • Anjali Tripathi,
  • Nidhi Gupta,
  • Akash yadav

摘要

Introduction

A solitary mass that may be sessile or pedunculated is the hallmark of a peripheral ossifying fibroma. The lesion typically measures less than 1.5 cm in diameter, but in rare cases, it may enlarge to sizes ranging from 6 to 9 cm. It is usually considered as a reactive lesion, with its origin believed to be from the periodontal ligament. This study aims to identify the factors contributing to the recurrence of Ossifying Fibroma, as well as those associated with favourable outcomes and the prevention of recurrence. This study underscores the importance of thorough surgical management and vigilant post-operative care in improving the prognosis of POF and minimizing the risk of recurrence.

Method

A retrospective view was done from Institute’s medical record department from January 2019 to December 2024. The following data was obtained from the lesion; age at presentation, gender, site and size of the lesion, radiographic presentation (locularity), presence of irritants and local inflammatory factors, systemic health of the patient and post-op care. Patients were monitored regularly and followed for 5 years to assess for potential recurrence of the lesion.

Result

This retrospective observational cohort study evaluated 43 patients clinically and radiographically diagnosed with ossifying fibroma, with a mean age of 38.88 years and a female predominance (67.4%). Mandibular (62.8%) and posterior jaw (62.8%) involvement were most frequent. Radiographically, unilocular (55.8%) and mixed radiolucent-radiopaque (62.8%) patterns were more common. Recurrence was observed in 18.6% of cases. A significant correlation was noted between gender and confounding factors (p = 0.038). Lesion size averaged 6.62 cm, with larger lesions potentially linked to higher recurrence risk.

Conclusion

Ossifying fibroma demonstrates a predilection for females in the third to fifth decades of life, with a marked tendency for mandibular and posterior jaw involvement. Radiographically, the majority of lesions exhibited a unilocular architecture with a characteristic mixed radiolucent-radiopaque pattern. Recurrence was documented in 18.6% of cases; however, no statistically significant associations were found with site, radiographic features, or systemic health. A noteworthy correlation was identified between gender and the presence of confounding factors, potentially indicating an increased susceptibility to lesion recurrence in affected patients. These findings underscore the importance of vigilant clinical and radiographic surveillance to effectively monitor and manage the potential for recurrence in ossifying fibroma cases.