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<p>Schwannomas are most commonly seen in the second and third decades of life and are usually solitary. Here, we report a case of a young girl presenting with an ulcerated mass in the palate. A 15-year-old female presented with painless, gradually enlarging oral cavity swelling over six months. Examination revealed a 4 × 4&#xa0;cm non-tender, firm and ulcerated midline swelling on the soft palate, displacing the uvula posteriorly. Imaging demonstrated a well-circumscribed, mildly enhancing mass in soft palate. A prior biopsy suggested acute inflammatory lesion. Lesion was excised with 1&#xa0;cm margins. Histopathological examination (HPE) revealed a biphasic tumor with Antoni A and Antoni B areas, Verocay bodies, and strong immunopositivity for S100 protein and SOX-10, confirming the diagnosis of schwannoma. Postoperative recovery was uneventful and is on regular follow-up. Palatal schwannomas are rare and require histopathological confirmation for accurate diagnosis. Complete surgical excision ensures excellent prognosis with minimal recurrence risk.</p>

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A Case Report and Literature Review on a Rare Differential Diagnosis of Palatal Swelling: Palatal Schwannoma

  • 期刊论文

  • 发表日期：

    2026年2月24日

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  • Aasma Nalwa,
  • Nithin Prakasan Nair,
  • Sudeep Khera,
  • Darwin Kaushal

摘要

Schwannomas are most commonly seen in the second and third decades of life and are usually solitary. Here, we report a case of a young girl presenting with an ulcerated mass in the palate. A 15-year-old female presented with painless, gradually enlarging oral cavity swelling over six months. Examination revealed a 4 × 4 cm non-tender, firm and ulcerated midline swelling on the soft palate, displacing the uvula posteriorly. Imaging demonstrated a well-circumscribed, mildly enhancing mass in soft palate. A prior biopsy suggested acute inflammatory lesion. Lesion was excised with 1 cm margins. Histopathological examination (HPE) revealed a biphasic tumor with Antoni A and Antoni B areas, Verocay bodies, and strong immunopositivity for S100 protein and SOX-10, confirming the diagnosis of schwannoma. Postoperative recovery was uneventful and is on regular follow-up. Palatal schwannomas are rare and require histopathological confirmation for accurate diagnosis. Complete surgical excision ensures excellent prognosis with minimal recurrence risk.