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<p>Myopericytoma (MPC) is a rare benign perivascular soft tissue tumour characterised by concentric proliferation of spindle-shaped myoid cells. It is typically seen in the extremities, with limited reports from the head and neck region. We present the first documented case of vallecular myopericytoma in a 39-year-old female who presented with a three-month history of foreign body sensation in the throat. Radiological evaluation revealed a well-defined, highly vascular vallecular mass, which was completely excised endoscopically using coblation. Histopathology and immunohistochemistry confirmed the diagnosis of MPC. The patient’s postoperative recovery and six-month follow-up were uneventful. This case highlights the diagnostic challenge of MPC in the upper aerodigestive tract due to its rarity and overlapping features with other vascular tumours. Complete surgical excision with negative margins remains the cornerstone of management. Further case accumulation and molecular studies are warranted to refine diagnostic criteria and management protocols.</p>

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Rare Occurrence of Myopericytoma in Vallecula: A Case Report

  • 期刊论文

  • 发表日期：

    2025年12月12日

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  • J. Poongkamali,
  • Balaji Ramamourthy,
  • V. Gayatheri,
  • K. N. Sivasreedhar

摘要

Myopericytoma (MPC) is a rare benign perivascular soft tissue tumour characterised by concentric proliferation of spindle-shaped myoid cells. It is typically seen in the extremities, with limited reports from the head and neck region. We present the first documented case of vallecular myopericytoma in a 39-year-old female who presented with a three-month history of foreign body sensation in the throat. Radiological evaluation revealed a well-defined, highly vascular vallecular mass, which was completely excised endoscopically using coblation. Histopathology and immunohistochemistry confirmed the diagnosis of MPC. The patient’s postoperative recovery and six-month follow-up were uneventful. This case highlights the diagnostic challenge of MPC in the upper aerodigestive tract due to its rarity and overlapping features with other vascular tumours. Complete surgical excision with negative margins remains the cornerstone of management. Further case accumulation and molecular studies are warranted to refine diagnostic criteria and management protocols.