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<p>Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) comprise the vast majority of the differentiated thyroid carcinomas, and oncocytic carcinoma contributes to about 3–5% cases. However, synchronous thyroid carcinomas are rare and commonly discovered incidentally and pose a therapeutic challenge. Herein, we describe a case of a 55-year-old female who presented with an anterior neck swelling of 6 months duration, which was gradually increasing in size. An imaging diagnosis of solitary nodule of the right thyroid lobe with no lymphadenopathy led to the pre-operative FNAC evaluation that demonstrated an oncocytic neoplasm. Right hemithyroidectomy was performed, and a histological diagnosis of OC of the right lobe was rendered. Completion thyroidectomy of the left lobe was performed, and histopathological evaluation of the left lobe revealed an incidental classic PTC microcarcinoma. Post-operative radioiodine therapy was given, and the patient has been on regular clinical follow-up for the last year. With this case, we want to highlight the need for the establishment of evidence-based guidelines for synchronous carcinomas of the thyroid for appropriate and targeted management of such patients.</p>

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Synchronous Papillary and Oncocytic Thyroid Carcinomas: An Unusual Occurrence

  • 期刊论文

  • 发表日期：

    2025年10月18日

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  • Manjit Kaur Rana,
  • Ankita Soni,
  • Gargi Kapatia,
  • Vikasdeep Gupta

摘要

Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) comprise the vast majority of the differentiated thyroid carcinomas, and oncocytic carcinoma contributes to about 3–5% cases. However, synchronous thyroid carcinomas are rare and commonly discovered incidentally and pose a therapeutic challenge. Herein, we describe a case of a 55-year-old female who presented with an anterior neck swelling of 6 months duration, which was gradually increasing in size. An imaging diagnosis of solitary nodule of the right thyroid lobe with no lymphadenopathy led to the pre-operative FNAC evaluation that demonstrated an oncocytic neoplasm. Right hemithyroidectomy was performed, and a histological diagnosis of OC of the right lobe was rendered. Completion thyroidectomy of the left lobe was performed, and histopathological evaluation of the left lobe revealed an incidental classic PTC microcarcinoma. Post-operative radioiodine therapy was given, and the patient has been on regular clinical follow-up for the last year. With this case, we want to highlight the need for the establishment of evidence-based guidelines for synchronous carcinomas of the thyroid for appropriate and targeted management of such patients.