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<p>Though papillary and follicular carcinomas are individually common thyroid malignancies, concurrent follicular-papillary lesions are rare, where two histologically-distinct synchronous primary neoplasms coincide at the same location. We are reporting a thyroid collision tumour combining papillary and angio-invasive follicular carcinoma which was diagnosed postoperatively via histopathology. The case highlights diagnostic challenges due to unclear preoperative indicators, and the need for individualized treatment. Surgical excision, radioiodine therapy, and thyroxine suppression led to a disease-free outcome for 8 years, emphasizing multidisciplinary management.</p>

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Papillary-Follicular Collision Tumour of Thyroid: A Rare Clinical Entity

  • 期刊论文

  • 发表日期：

    2025年9月15日

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  • Purushottam Chavan,
  • Saud Ahmed,
  • Sreelekha Ray

摘要

Though papillary and follicular carcinomas are individually common thyroid malignancies, concurrent follicular-papillary lesions are rare, where two histologically-distinct synchronous primary neoplasms coincide at the same location. We are reporting a thyroid collision tumour combining papillary and angio-invasive follicular carcinoma which was diagnosed postoperatively via histopathology. The case highlights diagnostic challenges due to unclear preoperative indicators, and the need for individualized treatment. Surgical excision, radioiodine therapy, and thyroxine suppression led to a disease-free outcome for 8 years, emphasizing multidisciplinary management.