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<p>The objective of this study was to determine the role of vitamin D supplementation in reducing recurrence rates of BPPV and secondarily to study the association between saccular and utricular dysfunction, as seen on VEMP test, with vitamin D deficiency. A prospective randomized control trial was conducted over a period of 18&#xa0;months, with 66 BPPV patients with vitamin D deficiency. These patients were divided into two groups, a study and a control group. Dix Hallpike test was done to confirm the diagnosis of posterior canalithiasis benign paroxysmal positional vertigo, VEMP test and serum vitamin D level recorded at first visit. All patients were treated with canalith repositioning manoeuvres and the study group was treated additionally with vitamin D oral supplementation. Follow up done at 6&#xa0;weeks and 3&#xa0;months for recurrence of symptoms and VEMP test repeated at the end of 3&#xa0;months. The two groups were analysed with binary logistic regression analyses. The age and sex wise distribution in both study and control groups was statistically insignificant (P &gt; 0.05). In our study, supplementing vitamin D had no additional effect in reducing the rate of recurrence in BPPV (P &gt; 0.05). A significant association noted between VEMP abnormality and low serum vitamin D levels (P &lt; 0.05). This study also shows significant difference in the VEMP test done at first visit and repeat VEMP done at the end of 3&#xa0;months of follow up, in both study and control groups (P &lt; 0.05). To further reach a specific conclusion, we recommend more studies be carried out in this aspect with a larger sample size with follow up period of at least 1&#xa0;year.</p>

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A Prospective Analysis on Association Between Vitamin D3 Levels and Benign Paroxysmal Positional Vertigo and its Correlation with Vestibular Evoked Myogenic Potentials

  • 期刊论文

  • 发表日期：

    2025年9月8日

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  • S. Sandeep,
  • Iruvantika Malik,
  • C. Shilpa

摘要

The objective of this study was to determine the role of vitamin D supplementation in reducing recurrence rates of BPPV and secondarily to study the association between saccular and utricular dysfunction, as seen on VEMP test, with vitamin D deficiency. A prospective randomized control trial was conducted over a period of 18 months, with 66 BPPV patients with vitamin D deficiency. These patients were divided into two groups, a study and a control group. Dix Hallpike test was done to confirm the diagnosis of posterior canalithiasis benign paroxysmal positional vertigo, VEMP test and serum vitamin D level recorded at first visit. All patients were treated with canalith repositioning manoeuvres and the study group was treated additionally with vitamin D oral supplementation. Follow up done at 6 weeks and 3 months for recurrence of symptoms and VEMP test repeated at the end of 3 months. The two groups were analysed with binary logistic regression analyses. The age and sex wise distribution in both study and control groups was statistically insignificant (P > 0.05). In our study, supplementing vitamin D had no additional effect in reducing the rate of recurrence in BPPV (P > 0.05). A significant association noted between VEMP abnormality and low serum vitamin D levels (P < 0.05). This study also shows significant difference in the VEMP test done at first visit and repeat VEMP done at the end of 3 months of follow up, in both study and control groups (P < 0.05). To further reach a specific conclusion, we recommend more studies be carried out in this aspect with a larger sample size with follow up period of at least 1 year.