Scholarlink

Introduction <p>In cases of spontaneous CSF rhinorrhea, the endoscopic repair using Hadad flap is the gold standard treatment. It is augmented with synthetic fibrin sealants to increase the success rates. We propose autologous fibrin sealants for the same with similar results.</p> Method <p>10 patients with spontaneous CSF rhinorrhea who underwent endoscopic CSF leak repair with Hadad flap was augmented with Platelet rich fibrin (PRF) and plasma (PRP).The post-operative healing was noted and followed up for a period of one and a half year.</p> Result <p>The healing was satisfactory and comparable to synthetic sealants in all patients.</p> Discussion <p>Many studies have established the efficiency of synthetic fibrin glue as an adjuvant in the CSF leak repair. However, cost concerns, local stock availability, difficulty in mixing and application and less quantity per pack limit its use. These can be overcome with the autologous fibrin sealants with comparable results.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Platelet Rich Fibrin(PRF) and Platelet Rich Plasma (PRP) in Endoscopic Cerebro Spinal Fluid (CSF) Rhinorrhoea Repair: A Novel Alternative to Synthetic Fibrin Sealant

  • 期刊论文

  • 发表日期：

    2025年9月18日

查看全文
  • Vinod Felix,
  • A. Lakshmi,
  • Sanooja Pinki,
  • C. Jyothi

摘要

Introduction

In cases of spontaneous CSF rhinorrhea, the endoscopic repair using Hadad flap is the gold standard treatment. It is augmented with synthetic fibrin sealants to increase the success rates. We propose autologous fibrin sealants for the same with similar results.

Method

10 patients with spontaneous CSF rhinorrhea who underwent endoscopic CSF leak repair with Hadad flap was augmented with Platelet rich fibrin (PRF) and plasma (PRP).The post-operative healing was noted and followed up for a period of one and a half year.

Result

The healing was satisfactory and comparable to synthetic sealants in all patients.

Discussion

Many studies have established the efficiency of synthetic fibrin glue as an adjuvant in the CSF leak repair. However, cost concerns, local stock availability, difficulty in mixing and application and less quantity per pack limit its use. These can be overcome with the autologous fibrin sealants with comparable results.