<p>To investigate the prevalence of oropharyngeal dysphagia, laryngopharyngeal reflux (LPR), and job burnout among adult patients with obstructive sleep apnea syndrome (OSAS) and assess their associations with the apnea-hypopnea index (AHI).This cross-sectional study was conducted on 200 adult patients diagnosed with OSAS. Participants underwent sleep studies, clinical assessments including body mass index (BMI), and completed the Arabic versions of the the Eating Assessment Tool (EAT-10), Reflux Symptom Index (RSI), and the Maslach Burnout Inventory (MBI). Correlations between AHI and RSI, EAT-10, and MBI scores were analyzed using Spearman’s correlation. Among 200 patients (68% males; mean age 44 ± 10&#xa0;years; mean BMI 29.5 ± 4.4&#xa0;kg/m²), the median AHI was 27 (range 9–70), with 24% mild, 32% moderate, and 44% severe OSAS. The mean RSI was 21 ± 7 and mean EAT-10 score was 26 ± 8. High burnout levels were observed in 48% (occupational exhaustion) and 34% (depersonalization), with 82% reporting low personal accomplishment. AHI correlated positively with RSI (r = 0.855, <i>p &lt; </i>0.001), EAT-10 (r = 0.788, <i>p &lt; </i>0.001), occupational exhaustion (r = 0.388, <i>p &lt; </i>0.001), depersonalization (r = 0.404, <i>p &lt; </i>0.001), andnegatively with personal accomplishment (r = −&#xa0;0.211, <i>p = </i>0.003). Multivariate regression showed that each unit increase in AHI predicted increases in RSI (B = 0.254, <i>p &lt; </i>0.001), EAT-10 (B = 0.267, <i>p &lt; </i>0.001), occupational exhaustion (B = 0.396, <i>p &lt; </i>0.001), and depersonalization scores (B = 0.171, <i>p &lt; </i>0.001). Oropharyngeal dysphagia, LPR, and job burnout are prevalent among OSAS patients and are significantly associated with AHI severity.</p>