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<p>Though myringoplasty is established as a common procedure, failures have been reported in literature. This encourages the need to explore other options besides the autologous graft materials which may have been expended in the initial surgery. Collagen is one such versatile material. The closure of small to medium sized residual and recurrent tympanic membrane perforations using collagen patch on 50 patients were studied. These patients had previously undergone microscopic myringoplasty using temporalis fascia grafting. Pure Tone Audiometry and otoendoscopy were the two parameters used to assess the outcome. Complete closure of tympanic membrane perforation was noted in 41 cases. Success rate of 84% was achieved. Pre-operative Air Bone Gap (ABG) was in the range of 15–24.3 dB with average ABG 21.9 dB and the post-operative ABG was in the range of 5–16.2dB with average 10.7 db. The average hearing improvement in the form of closure of ABG was 10.8 dB (<i>p</i> &lt; 0.001). Since collagen is the constituent of the normal tympanic membrane, considering it as a viable option is justified. This could be beneficial to patients with residual and recurrent perforations where temporalis fascia may not be available. Endoscopic transcanal collagen myringoplasty may be used as a quicker procedure with a lower morbidity as compared to conventional procedures. The success rate is less compared to autografts like temporalis fascia and tragal perichondrium. Hence this graft can be considered as a viable option in recurrent or residual perforations where temporalis fascia has already been harvested.</p>

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Collagen Grafting: Is it an Option in Myringoplasty for Residual Perforations?

  • 期刊论文

  • 发表日期：

    2025年6月28日

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  • M D Prakash,
  • N B Varsha

摘要

Though myringoplasty is established as a common procedure, failures have been reported in literature. This encourages the need to explore other options besides the autologous graft materials which may have been expended in the initial surgery. Collagen is one such versatile material. The closure of small to medium sized residual and recurrent tympanic membrane perforations using collagen patch on 50 patients were studied. These patients had previously undergone microscopic myringoplasty using temporalis fascia grafting. Pure Tone Audiometry and otoendoscopy were the two parameters used to assess the outcome. Complete closure of tympanic membrane perforation was noted in 41 cases. Success rate of 84% was achieved. Pre-operative Air Bone Gap (ABG) was in the range of 15–24.3 dB with average ABG 21.9 dB and the post-operative ABG was in the range of 5–16.2dB with average 10.7 db. The average hearing improvement in the form of closure of ABG was 10.8 dB (p < 0.001). Since collagen is the constituent of the normal tympanic membrane, considering it as a viable option is justified. This could be beneficial to patients with residual and recurrent perforations where temporalis fascia may not be available. Endoscopic transcanal collagen myringoplasty may be used as a quicker procedure with a lower morbidity as compared to conventional procedures. The success rate is less compared to autografts like temporalis fascia and tragal perichondrium. Hence this graft can be considered as a viable option in recurrent or residual perforations where temporalis fascia has already been harvested.