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<p>Central Giant Cell Granuloma (CGCG) is a rare, benign yet locally aggressive lesion that most commonly affects the jaws, particularly the mandible. CGCG is an uncommon finding in the hard palate, with few cases reported in the literature. Trauma has been proposed as a potential risk factor for its development. A 14-year-old female presented with a slowly enlarging, painless swelling on the right side of the hard palate, which developed two months after undergoing septoplasty and bilateral partial inferior turbinectomy. Radiological examination, including Computed Tomography (CT) and nasal endoscopy, revealed an osteolytic mass eroding the hard palate and extending into the right nasal floor, reaching the inferior turbinate. The lesion was excised surgically using a transoral approach with endoscopic assistance to prevent damage to the nasal mucosa. Histopathological analysis confirmed the diagnosis of CGCG. This case emphasizes the importance of considering CGCG in the differential diagnoses of palatal swellings, particularly after nasal surgeries. Early diagnosis, meticulous surgical planning, and long-term follow-up are crucial for optimal management. Endoscopy during surgery helps preserve surrounding structures and ensure complete lesion excision. The multidisciplinary approach is fundamental for the management of such lesions.</p>

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Central Giant Cell Granuloma of Hard Palate: A Rare Complication Post Nasal Surgery

  • 期刊论文

  • 发表日期：

    2025年6月28日

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  • Sobhy Khaled,
  • Saad Elzayat,
  • Mohamed Mohamed Hussein,
  • Ahmed Ebeed,
  • Ahmed S. Abdelhamid

摘要

Central Giant Cell Granuloma (CGCG) is a rare, benign yet locally aggressive lesion that most commonly affects the jaws, particularly the mandible. CGCG is an uncommon finding in the hard palate, with few cases reported in the literature. Trauma has been proposed as a potential risk factor for its development. A 14-year-old female presented with a slowly enlarging, painless swelling on the right side of the hard palate, which developed two months after undergoing septoplasty and bilateral partial inferior turbinectomy. Radiological examination, including Computed Tomography (CT) and nasal endoscopy, revealed an osteolytic mass eroding the hard palate and extending into the right nasal floor, reaching the inferior turbinate. The lesion was excised surgically using a transoral approach with endoscopic assistance to prevent damage to the nasal mucosa. Histopathological analysis confirmed the diagnosis of CGCG. This case emphasizes the importance of considering CGCG in the differential diagnoses of palatal swellings, particularly after nasal surgeries. Early diagnosis, meticulous surgical planning, and long-term follow-up are crucial for optimal management. Endoscopy during surgery helps preserve surrounding structures and ensure complete lesion excision. The multidisciplinary approach is fundamental for the management of such lesions.