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<p>Post-extubation stridor is a common airway-related complication often seen in critical care units. It is frequently associated with laryngeal edema following prolonged intubation. Laryngeal injuries during intubation can trigger an inflammatory response, leading to varying degrees of edema and potentially causing stridor after extubation. We report a case of a 41-year-old female who required intubation and prolonged mechanical ventilation due to traumatic brain injury. The trachea was extubated five days after the injury when her GCS improved to E4VtM6. After extubation, she developed stridor, which was successfully managed with 3% hypertonic saline nebulisation. Hypertonic saline (3% or 6%) is often used in the treatment of conditions such as cystic fibrosis and bronchiectasis as a mucolytic agent. This article aims to highlight hypertonic saline nebulisation as a new treatment approach in managing laryngeal oedema and post-extubation stridor.</p>

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Hypertonic Saline Nebulisation as a Therapeutic Intervention for Post-Extubation Stridor - A Novel Use of an Existing Cure

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • Sivakumar Ramalingam,
  • Chandini Kukanti,
  • Pharanitharan Natarajan

摘要

Post-extubation stridor is a common airway-related complication often seen in critical care units. It is frequently associated with laryngeal edema following prolonged intubation. Laryngeal injuries during intubation can trigger an inflammatory response, leading to varying degrees of edema and potentially causing stridor after extubation. We report a case of a 41-year-old female who required intubation and prolonged mechanical ventilation due to traumatic brain injury. The trachea was extubated five days after the injury when her GCS improved to E4VtM6. After extubation, she developed stridor, which was successfully managed with 3% hypertonic saline nebulisation. Hypertonic saline (3% or 6%) is often used in the treatment of conditions such as cystic fibrosis and bronchiectasis as a mucolytic agent. This article aims to highlight hypertonic saline nebulisation as a new treatment approach in managing laryngeal oedema and post-extubation stridor.