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Aims <p>Menière’s Disease (MD) is an inner ear disorder in which raised endolympathic volume is the commonly accepted pathophysiological mechanism. After the development of qualitative grading of hydrops in magnetic resonance imaging (MRI), authors tried to correlate the imaging findings with clinical data, with different findings. Aim of our work was to assess if the MRI grading correlates with the severity of clinical findings collected in a sample of MD subjects not reporting vertigo and \ or hearing fluctuation in the period between bedside examination and MRI.</p> Materials and Methods <p>We enrolled 44 patients during the period between January 2023 and September 2024 who performed an audiometric exam, a vestibular bedside examination and 3D-FLAIR and delayed post contrast MRI for detecting endolymphatic hydrops. To correlate the MRI staging of hydrops with cochlear and vestibular variables a Pearson test was performed.</p> Results <p>No correlation has been found between hydrops grading and duration of the disease for both cochlear (<i>p</i> = 0.08) and vestibular part (<i>p</i> = 0.9). A strong correlation was detected between hearing level and cochlear imaging findings (<i>p</i> &lt; 0.0001) while no correlation has been found between signs of vestibular deficit and the grading of the vestibule.</p> Conclusion <p>No correlation has been found between MRI grading of the disease and its duration in years, which partially confirm how MD is an impredictable condition. Our data also suggest the hypotesis that the cochlear part plays the most important role in the evolution of the disorder, with a strong correlation between hearing level and cochlear imaging findings.</p>

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Correlation between Cochleovestibular Phenotypes of Menière’s Disease and Inner Ear Imaging on 3D FLAIR Delayed Post-Contrast MRI

  • 期刊论文

  • 发表日期：

    2025年6月6日

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  • Roberto Teggi,
  • Iacopo Cangiano,
  • Davide Toscano,
  • Alessandro Nobile,
  • Alberto Diena,
  • Andrea Falini,
  • Anna Del Poggio

摘要

Aims

Menière’s Disease (MD) is an inner ear disorder in which raised endolympathic volume is the commonly accepted pathophysiological mechanism. After the development of qualitative grading of hydrops in magnetic resonance imaging (MRI), authors tried to correlate the imaging findings with clinical data, with different findings. Aim of our work was to assess if the MRI grading correlates with the severity of clinical findings collected in a sample of MD subjects not reporting vertigo and \ or hearing fluctuation in the period between bedside examination and MRI.

Materials and Methods

We enrolled 44 patients during the period between January 2023 and September 2024 who performed an audiometric exam, a vestibular bedside examination and 3D-FLAIR and delayed post contrast MRI for detecting endolymphatic hydrops. To correlate the MRI staging of hydrops with cochlear and vestibular variables a Pearson test was performed.

Results

No correlation has been found between hydrops grading and duration of the disease for both cochlear (p = 0.08) and vestibular part (p = 0.9). A strong correlation was detected between hearing level and cochlear imaging findings (p < 0.0001) while no correlation has been found between signs of vestibular deficit and the grading of the vestibule.

Conclusion

No correlation has been found between MRI grading of the disease and its duration in years, which partially confirm how MD is an impredictable condition. Our data also suggest the hypotesis that the cochlear part plays the most important role in the evolution of the disorder, with a strong correlation between hearing level and cochlear imaging findings.