Scholarlink

<p>Cholesterol granuloma is a rare, benign lesion of the mastoid air cells, often associated with glue ear and typically presenting unilaterally. Histopathologically, it comprises of granulation tissue with cholesterol crystals, multinucleated giant cells, and hemosiderin deposits from erythrocyte breakdown. While commonly found in the petrous apex, tympanomastoid cholesterol granulomas are rare, with very few cases reported in literature. It can mimic other otological conditions, leading to diagnostic challenges. We report a rare case of cholesterol granuloma presenting as acute mastoiditis in a 24-year-old female with type 1 diabetes. She presented with postauricular swelling, pain, fever, and hearing loss. Imaging revealed a cystic lesion with bony erosion in the mastoid antrum. Surgical exploration uncovered a lobulated cyst containing thick fluid, which was managed via marsupialization and reconstruction. Histopathology confirmed the diagnosis of cholesterol granuloma. This case underscores the need for clinical suspicion of rare pathologies in chronic otitis media cases and highlights the importance of timely intervention to prevent complications.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A Diagnostic Enigma: A Rare Case of Cholesterol Granuloma of Mastoid Masquerading as Acute Mastoiditis in a Young Female

  • 期刊论文

  • 发表日期：

    2025年5月20日

查看全文
  • Anupam V. Mohan,
  • Sandeep Dabhekar,
  • Dharanya Gopalakrishnan Srinivasan,
  • Nisha Meshram,
  • Vijay Bidkar,
  • Kiran Kumar Prathipati,
  • Nittika Garg

摘要

Cholesterol granuloma is a rare, benign lesion of the mastoid air cells, often associated with glue ear and typically presenting unilaterally. Histopathologically, it comprises of granulation tissue with cholesterol crystals, multinucleated giant cells, and hemosiderin deposits from erythrocyte breakdown. While commonly found in the petrous apex, tympanomastoid cholesterol granulomas are rare, with very few cases reported in literature. It can mimic other otological conditions, leading to diagnostic challenges. We report a rare case of cholesterol granuloma presenting as acute mastoiditis in a 24-year-old female with type 1 diabetes. She presented with postauricular swelling, pain, fever, and hearing loss. Imaging revealed a cystic lesion with bony erosion in the mastoid antrum. Surgical exploration uncovered a lobulated cyst containing thick fluid, which was managed via marsupialization and reconstruction. Histopathology confirmed the diagnosis of cholesterol granuloma. This case underscores the need for clinical suspicion of rare pathologies in chronic otitis media cases and highlights the importance of timely intervention to prevent complications.