<p>Satisfaction level after cosmetic surgery, creating unrealistic expectations, and hiding other complications of the surgery. The present study aims to investigate the relationship between personality patterns and the general health of rhinoplasty applicants with the post-operative satisfaction of clients. His cross-sectional study was conducted on 57 applicants for rhinoplasty and 57 control subjects after age and gender matching. The control group was selected from relatives of rhinoplasty applicants to control cultural and genetic factors. Data was collected using general health questionnaire-28 (GHQ-28), NEO Five-Factor Inventory (NEO-FFI) questionnaire, and satisfaction with surgery. The data were analyzed using SPSS.24 software and a significance level of 0.05. The mean age of rhinoplasty applicants was 29.84 ± 8.02 years and for the control group was 30.49 ± 7.75 years (<i>P</i> = 0.661). The frequency of women applying for rhinoplasty was 71.9% (<i>P</i> = 0.836). The odds ratio for rhinoplasty decreased by increasing agreeableness (OR: 0.741, 95% CI: 0.598–0.917) and by increasing levels of neuroticism (OR: 1.523, 95% CI: 1.225–1.894) and extraversion (OR: 1.291, 95% CI: 1.091–1.527) increased. By increasing anxiety, the odds ratio of rhinoplasty surgery decreased (OR: 0.823, 95% CI: 0.696–0.975). Those who had higher neuroticism had lower satisfaction with rhinoplasty by 0.679 (<i>P</i> &lt; 0.001). Different dimensions of personality and general health of people affect the action and tendency towards rhinoplasty. It is necessary to check the health level of applicants for rhinoplasty and also perform psychiatric consultations to check the causes of performing rhinoplasty and prevent unnecessary surgeries.</p>