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<p>Extranodal NK/T cell lymphoma nasal type (ENKTL-NT) is a rare and aggressive subtype of Non-Hodgkin’s lymphoma (NHL) involving the midline structures of the face and upper aero digestive tract. While its pathogenesis is strongly associated with Epstein-Barr virus (EBV), the coexistence of fungal infections in ENKTL-NT is also seen and poses significant diagnostic and therapeutic challenges. This paper is an attempt to report the case of a 48 year old female from Nagaland, India with EBV positive ENKTL-NT co-infected with unusual fungal species <i>Fonsecaea pedrosoi</i>. It is one of such first cases reported from this part of the country, highlighting the diagnostic challenges, rapid progression and high mortality characteristic of this condition.</p>

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Nasal NK/T-Cell Lymphoma with Unusual Fonsecaea pedrosoi Infection: A Rare Case Report from Northeast India

  • 期刊论文

  • 发表日期：

    2025年4月8日

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  • Medozhanuo Solo,
  • Neiluotuonuo Solo

摘要

Extranodal NK/T cell lymphoma nasal type (ENKTL-NT) is a rare and aggressive subtype of Non-Hodgkin’s lymphoma (NHL) involving the midline structures of the face and upper aero digestive tract. While its pathogenesis is strongly associated with Epstein-Barr virus (EBV), the coexistence of fungal infections in ENKTL-NT is also seen and poses significant diagnostic and therapeutic challenges. This paper is an attempt to report the case of a 48 year old female from Nagaland, India with EBV positive ENKTL-NT co-infected with unusual fungal species Fonsecaea pedrosoi. It is one of such first cases reported from this part of the country, highlighting the diagnostic challenges, rapid progression and high mortality characteristic of this condition.