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<p>Immunoglobulin G4-related disease is a chronic fibro-inflammatory condition characterized by raised serum IgG4 concentrations, which with tissue infiltration by IgG4 plasma cells leads to pseudotumor formation in various organs. Primary presentation is very rare and is life threatening. This is only the 16th reported case of Immunoglobulin G4-related disease with primary laryngeal involvement worldwide and is the first reported case in the Indian population.</p>

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Laryngeal Manifestation of Immunoglobulin G4-Related Disease: An Elusive Life-Threatening Entity

  • 期刊论文

  • 发表日期：

    2025年3月27日

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  • Sakshi Negi,
  • Monil Parsana,
  • Vikas Sharma,
  • Naresh Kumar Panda,
  • Kirti Gupta

摘要

Immunoglobulin G4-related disease is a chronic fibro-inflammatory condition characterized by raised serum IgG4 concentrations, which with tissue infiltration by IgG4 plasma cells leads to pseudotumor formation in various organs. Primary presentation is very rare and is life threatening. This is only the 16th reported case of Immunoglobulin G4-related disease with primary laryngeal involvement worldwide and is the first reported case in the Indian population.