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<p>We present two rare thyroid cancer cases, Hyalinizing trabecular tumor (HTT) and Warthin-like papillary thyroid carcinoma (WL-PTC) coexisting with an oncocytic PTC variant. A 64-year-old female patient presented with a 26 × 11.1&#xa0;mm isoechoic thyroid nodule on ultrasound. Fine needle aspiration (FNA) cytology showed atypia of undetermined significance (TBS III). Three years later, new FNA cytology showed ‘’suspicious of malignancy (TBS V)’’. The patient was thyroidectomized and pathology revealed HTT. The second patient, a 54-year-old woman presented with a 13&#xa0;mm ultrasound thyroid nodule with irregular borders and microcalcifications. FNA cytology showed PTC, possibly a tall cell variant (TBS VI). The patient underwent thyroidectomy and pathology revealed WL-PTC coexisting with an oncocytic PTC variant. After radioiodine ablation the patient began levothyroxine therapy.</p>

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Hyalinizing Trabecular Tumor and Warthin Like Variant Coexisting with an Oncocytic Variant of Papillary Carcinoma: Two Case Reports of Rare Thyroid Cancer Types

  • 期刊论文

  • 发表日期：

    2025年3月24日

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  • Stavroula Psachna,
  • Evangelia Vogiatzi,
  • Dimitrios Ioannidis,
  • Dimitrios Lilis,
  • Maria Drakou,
  • Stavroula A. Paschou,
  • Christina Zoumpouli,
  • Nikolaos Goutas,
  • Antonis Polymeris

摘要

We present two rare thyroid cancer cases, Hyalinizing trabecular tumor (HTT) and Warthin-like papillary thyroid carcinoma (WL-PTC) coexisting with an oncocytic PTC variant. A 64-year-old female patient presented with a 26 × 11.1 mm isoechoic thyroid nodule on ultrasound. Fine needle aspiration (FNA) cytology showed atypia of undetermined significance (TBS III). Three years later, new FNA cytology showed ‘’suspicious of malignancy (TBS V)’’. The patient was thyroidectomized and pathology revealed HTT. The second patient, a 54-year-old woman presented with a 13 mm ultrasound thyroid nodule with irregular borders and microcalcifications. FNA cytology showed PTC, possibly a tall cell variant (TBS VI). The patient underwent thyroidectomy and pathology revealed WL-PTC coexisting with an oncocytic PTC variant. After radioiodine ablation the patient began levothyroxine therapy.