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Introduction <p>Malignancy of parotid glands is uncommon in the pediatric age group. Among the various subtypes, mammary analogue secretory carcinoma (MASC) of parotid is an unusual variant that mimics pathologically those of mammary secretory carcinoma of the breast. It usually presents as a slow-growing, painless parotid mass.</p> Case Summary <p>We had a 17-year-old female patient who presented with recurrent swelling in her right parotid region, which was adherent to the skin focally. Contrast-enhanced MR showed a solid multi-cystic lesion in her right parotid region. Pre-operative cytopathology was inconclusive. She underwent total parotidectomy with level II nodal clearance, and the histopathology was suggestive of mammary analogue secretory carcinoma.</p> Discussion <p>MASC is considered to be a low-grade, slow-growing malignancy when presented at an earlier stage. Our patient was kept under close follow-up, and she is disease-free at nearly thirty months post-operatively.</p>

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Mammary Analogue Secretory Carcinoma of the Parotid at Younger Age: An Unusual Entity

  • 期刊论文

  • 发表日期：

    2025年2月1日

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  • Dillip Kumar Samal,
  • Pradipta K. Parida,
  • Amit Kumar Adhya,
  • Pradeep Pradhan

摘要

Introduction

Malignancy of parotid glands is uncommon in the pediatric age group. Among the various subtypes, mammary analogue secretory carcinoma (MASC) of parotid is an unusual variant that mimics pathologically those of mammary secretory carcinoma of the breast. It usually presents as a slow-growing, painless parotid mass.

Case Summary

We had a 17-year-old female patient who presented with recurrent swelling in her right parotid region, which was adherent to the skin focally. Contrast-enhanced MR showed a solid multi-cystic lesion in her right parotid region. Pre-operative cytopathology was inconclusive. She underwent total parotidectomy with level II nodal clearance, and the histopathology was suggestive of mammary analogue secretory carcinoma.

Discussion

MASC is considered to be a low-grade, slow-growing malignancy when presented at an earlier stage. Our patient was kept under close follow-up, and she is disease-free at nearly thirty months post-operatively.