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<p>Neodymium-doped yttrium aluminum garnet (Nd:YAG) LASER bronchoscopy has emerged as an important modality in the management of central airway obstruction, particularly in resource-limited settings. We retrospectively reviewed patients who underwent Nd:YAG LASER bronchoscopy between 2021 and 2024 at a tertiary&#xa0;care referral center in Nepal. Demographic characteristics, lesion profile, procedural details, complications, and outcomes were analyzed. Twenty three patients&#xa0;(86.9% male, median age 34.5 years) underwent 33 LASER sessions&#xa0;during the study period. Shortness of breath on exertion (86.9%) was the most common symptom and median symptom duration before presenting to us was 3 months. Patients were referred from centers across Nepal (73.9% from tertiary and 26.1% from district hospitals).&#xa0;The trachea was the most common site of lesion (48%). Benign lesions (60.9% ) were frequent, with post-intubation tracheal stenosis being the most common diagnosis&#xa0;(21.7%). Use of laryngeal mask&#xa0;airway for airway access increased (75%) while rigid bronchoscopy decreased (75%) over the course of four years.&#xa0;A statistically significant reduction in the Cotton-Myer grade was observed following the intervention (<i>p</i> &lt; 0.001). Sixteen of 19&#xa0;(84.8%) intubated patients were extubated immediately after the procedure. Minor hypoxia, major hypoxia, and minor bleeding occurred in eight (24%), one (3%), and seven sessions (21%), respectively.&#xa0;No airway fire, major hemorrhage, or 30-day mortality occurred. Nd:YAG LASER bronchoscopy is a safe and effective intervention for diverse airway lesions and demonstrates feasibility in a tertiary care center setting.</p> Graphical abstract <p></p>

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Evaluation of neodymium-doped yttrium aluminum garnet (Nd:YAG) LASER bronchoscopy for airway lesions: a single-center experience

  • 期刊论文

  • 发表日期：

    2026年4月25日

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  • Ranjan Sapkota,
  • Prajjwol Luitel,
  • Amit Yadav,
  • Sangita Basnet Sapkota,
  • Sushan Man Shrestha,
  • Aakriti Sharma,
  • Bibhusal Thapa

摘要

Neodymium-doped yttrium aluminum garnet (Nd:YAG) LASER bronchoscopy has emerged as an important modality in the management of central airway obstruction, particularly in resource-limited settings. We retrospectively reviewed patients who underwent Nd:YAG LASER bronchoscopy between 2021 and 2024 at a tertiary care referral center in Nepal. Demographic characteristics, lesion profile, procedural details, complications, and outcomes were analyzed. Twenty three patients (86.9% male, median age 34.5 years) underwent 33 LASER sessions during the study period. Shortness of breath on exertion (86.9%) was the most common symptom and median symptom duration before presenting to us was 3 months. Patients were referred from centers across Nepal (73.9% from tertiary and 26.1% from district hospitals). The trachea was the most common site of lesion (48%). Benign lesions (60.9% ) were frequent, with post-intubation tracheal stenosis being the most common diagnosis (21.7%). Use of laryngeal mask airway for airway access increased (75%) while rigid bronchoscopy decreased (75%) over the course of four years. A statistically significant reduction in the Cotton-Myer grade was observed following the intervention (p < 0.001). Sixteen of 19 (84.8%) intubated patients were extubated immediately after the procedure. Minor hypoxia, major hypoxia, and minor bleeding occurred in eight (24%), one (3%), and seven sessions (21%), respectively. No airway fire, major hemorrhage, or 30-day mortality occurred. Nd:YAG LASER bronchoscopy is a safe and effective intervention for diverse airway lesions and demonstrates feasibility in a tertiary care center setting.

Graphical abstract