Scholarlink

<p>Factor XIII (FXIII) is the final enzyme in the coagulation cascade that cross-links the fibrin monomers, thereby enhancing the clot strength. Congenital FXIII deficiency is rare and is inherited in an autosomal recessive manner. FXIII deficiency may lead to bleeding, delayed wound healing, hence increasing the risk for any surgical intervention. Literature on patients undergoing cardiac surgery with FXIII deficiency is rare. Cardiac surgery poses a major risk in this setting, as it involves heparinization while performing the surgery. This increases the risk of bleeding. In this case report, we present a patient undergoing coronary artery bypass grafting (CABG) surgery with FXIII deficiency. In this report, we focus on the perioperative management of FXIII deficiency, intraoperative surgical management, and postoperative surgical care in a patient who underwent CABG surgery with FXIII deficiency as opposed to standard CABG procedure.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Coronary artery bypass grafting in a patient with factor XIII deficiency: case report and review of perioperative management

  • 期刊论文

  • 发表日期：

    2026年3月26日

查看全文
  • Sowmya Kanthimathinathan,
  • Phani Krishna Machiraju,
  • Louis Felix Sridhar,
  • Prabu Pandurangan,
  • Satya Prasad Namala,
  • Srujan Singanamala

摘要

Factor XIII (FXIII) is the final enzyme in the coagulation cascade that cross-links the fibrin monomers, thereby enhancing the clot strength. Congenital FXIII deficiency is rare and is inherited in an autosomal recessive manner. FXIII deficiency may lead to bleeding, delayed wound healing, hence increasing the risk for any surgical intervention. Literature on patients undergoing cardiac surgery with FXIII deficiency is rare. Cardiac surgery poses a major risk in this setting, as it involves heparinization while performing the surgery. This increases the risk of bleeding. In this case report, we present a patient undergoing coronary artery bypass grafting (CABG) surgery with FXIII deficiency. In this report, we focus on the perioperative management of FXIII deficiency, intraoperative surgical management, and postoperative surgical care in a patient who underwent CABG surgery with FXIII deficiency as opposed to standard CABG procedure.