A new synthesis of 7H-pyrrolo[3,2-f]quinoxaline derivatives by a one-pot, three-component reaction
摘要
An acid-catalyzed three-component reaction of arylglyoxals, quinoxalin-6-amine and 4-hydroxycoumarin is described, leading to the synthesis of new functionalized 7H-pyrrolo[3,2-f]quinoxaline derivatives with good yields. It has high synthetic efficiency and operational simplicity, and only water was generated as a byproduct.
Graphical abstractA new procedure for the synthesis of pyrrolo[3,2-f]quinoxaline derivatives.