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<p>The widespread use of zirconia-toughened alumina (ZTA) ceramics has stimulated extensive research aimed at improving their functional characteristics, reducing production costs, and simplifying manufacturing processes. This study presents, for the first time, the fabrication of ZTA ceramics using Al<sub>2</sub>O<sub>3</sub> powder synthesized by the electrical explosion of Al wire in an oxygen-containing atmosphere. The effects of preliminary heat treatment of the Al<sub>2</sub>O<sub>3</sub> powder and mechanical activation of ZrO<sub>2</sub>–Al<sub>2</sub>O<sub>3</sub> powder mixtures on the microstructure, phase composition, porosity, and microhardness of the resulting ZTA ceramics were investigated. Mechanical activation of the powder mixture increased the density of the sintered ceramics from 80 to 92%. In addition, the use of Al<sub>2</sub>O<sub>3</sub> powder heat-treated at 1280°C reduced the average grain size of Al<sub>2</sub>O<sub>3</sub> in the sintered ceramics from 0.8 to 0.6 μm and that of ZrO<sub>2</sub> from 1.0 to 0.5 μm. Using 3T3-L1 fibroblasts as a model system, the resulting ceramic samples were found to be bioinert and non-toxic. Cell viability, morphology, and proliferation on the ceramic surfaces were comparable to those observed in the control group cultured on tissue-culture plastic.</p>

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Application of electroexplosive Al2O3 nanopowder for production of bioinert ZTA ceramics

  • 期刊论文

  • 发表日期：

    2026年7月3日

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  • A S Lozhkomoev,
  • S O Kazantsev,
  • A S Buyakov,
  • M G Ostapenko,
  • E V Plotnikov,
  • D D Eskova,
  • E I Shibaeva,
  • E I Matulskaya,
  • E I Senkina,
  • Z Jiahao,
  • M G Krinitsyn,
  • M I Lerner

摘要

The widespread use of zirconia-toughened alumina (ZTA) ceramics has stimulated extensive research aimed at improving their functional characteristics, reducing production costs, and simplifying manufacturing processes. This study presents, for the first time, the fabrication of ZTA ceramics using Al2O3 powder synthesized by the electrical explosion of Al wire in an oxygen-containing atmosphere. The effects of preliminary heat treatment of the Al2O3 powder and mechanical activation of ZrO2–Al2O3 powder mixtures on the microstructure, phase composition, porosity, and microhardness of the resulting ZTA ceramics were investigated. Mechanical activation of the powder mixture increased the density of the sintered ceramics from 80 to 92%. In addition, the use of Al2O3 powder heat-treated at 1280°C reduced the average grain size of Al2O3 in the sintered ceramics from 0.8 to 0.6 μm and that of ZrO2 from 1.0 to 0.5 μm. Using 3T3-L1 fibroblasts as a model system, the resulting ceramic samples were found to be bioinert and non-toxic. Cell viability, morphology, and proliferation on the ceramic surfaces were comparable to those observed in the control group cultured on tissue-culture plastic.