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<p><i>Gastrointestinal stromal tumours (GIST)</i> are rare mesenchymal neoplasms comprising less than 1% tumours. Originating from the interstitial cells of Cajal. These mostly affect the stomach, followed by the small intestine. Among the small intestine, jejunal involvement is particularly uncommon and rare. They are present in the older population and are small in size. Giant forms, female gender, young population, and jejunal involvement are a combination of exceptionally rare entities individually and combined. We report this rare combination wherein a young female, brought dead to the emergency with a protruded abdomen with a deluded diagnosis of pregnancy at first instance, was sent for medicolegal autopsy, revealing a giant, ruptured, aggressively progressive jejunal GIST. Despite undergoing a biopsy, a definitive diagnosis was not achieved, delaying appropriate diagnosis, which ultimately led to death.</p>

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Giant jejunal gastrointestinal stromal tumour (GIST) in a young female: a fatal case of diagnostic delay revealed at autopsy

  • 期刊论文

  • 发表日期：

    2026年6月26日

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  • Sunita Das,
  • Utkal Keshari Suna,
  • Laxmi Dhurve,
  • Manoj Kumar Mohanty,
  • Sindhu Sudha Sahu,
  • Mukund Namdev Sable

摘要

Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms comprising less than 1% tumours. Originating from the interstitial cells of Cajal. These mostly affect the stomach, followed by the small intestine. Among the small intestine, jejunal involvement is particularly uncommon and rare. They are present in the older population and are small in size. Giant forms, female gender, young population, and jejunal involvement are a combination of exceptionally rare entities individually and combined. We report this rare combination wherein a young female, brought dead to the emergency with a protruded abdomen with a deluded diagnosis of pregnancy at first instance, was sent for medicolegal autopsy, revealing a giant, ruptured, aggressively progressive jejunal GIST. Despite undergoing a biopsy, a definitive diagnosis was not achieved, delaying appropriate diagnosis, which ultimately led to death.