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<p>Genetic markers of the Y chromosome are useful tools for exploring paternal lineage and are widely used in forensic DNA analysis and population genetics. While profiles of many populations based on Y-STR markers in human genomes are ample, haplotype data for the Yunnan Bai population are still scarce. The aim of this study was to examine the genetic diversity of a sample of 151 unrelated healthy Chinese Bai male individuals from Yunnan province through the Goldeneye<sup>™</sup> Y Plus PCR Amplification Kit. A total of 312 alleles and 130 haplotypes were detected, out of which 117 haplotypes were unique, and the allelic frequencies ranged from 0.0066 to 0.9735. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.9973 and 0.8609, respectively. The gene diversity (GD) ranged from 0.0519 (DYS645) to 0.9494 (DYS385). These results demonstrated that the Goldeneye<sup>™</sup> Y Plus panel had a high discriminatory power in the Chinese Bai ethnic group. Additionally, Population comparisons between the Yunnan Bai and 20 reference populations were analyzed via the AMOVA, MDS, and phylogenetic relationship reconstruction. It was observed that Yunnan Bai population had close genetic affinity with the Tibeto-Burman speaking populations in China.</p>

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Genetic characterization of the Bai population from Yunnan province in China based on Y-STR population data

  • 期刊论文

  • 发表日期：

    2026年3月4日

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  • Xiufeng Zhang,
  • Kunya Li,
  • Xinxin Liu

摘要

Genetic markers of the Y chromosome are useful tools for exploring paternal lineage and are widely used in forensic DNA analysis and population genetics. While profiles of many populations based on Y-STR markers in human genomes are ample, haplotype data for the Yunnan Bai population are still scarce. The aim of this study was to examine the genetic diversity of a sample of 151 unrelated healthy Chinese Bai male individuals from Yunnan province through the Goldeneye™ Y Plus PCR Amplification Kit. A total of 312 alleles and 130 haplotypes were detected, out of which 117 haplotypes were unique, and the allelic frequencies ranged from 0.0066 to 0.9735. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.9973 and 0.8609, respectively. The gene diversity (GD) ranged from 0.0519 (DYS645) to 0.9494 (DYS385). These results demonstrated that the Goldeneye™ Y Plus panel had a high discriminatory power in the Chinese Bai ethnic group. Additionally, Population comparisons between the Yunnan Bai and 20 reference populations were analyzed via the AMOVA, MDS, and phylogenetic relationship reconstruction. It was observed that Yunnan Bai population had close genetic affinity with the Tibeto-Burman speaking populations in China.