Purpose <p>This aims to study poisoning cases involving bromadiolone, its detection from biological samples, and treatment for the survival of the victim.</p> Methods <p>A literature survey on bromadiolone poisoning using Scopus, PubMed, and World Wide Web using relevant keywords, e.g. Bromadiolone poisoning, bromadiolone toxicology, poisoning treatment, bromadiolone detection, detection methods. The analytical methods like thin layer chromatography, high performance liquid chromatography, gas chromatography, CT scans (computed tomography scan) Magnetic Resonance Imaging (MRI) and combined mass spectroscopic methods were used for the detection of bromadiolone.</p> Results <p>Bromadiolone poisoning in different organisms like cats, rats, birds, foxes, and human beings was studied. On the basis of the concentration of bromadiolone and its half-life period, symptoms like internal hemorrhage were observed; in some cases, lesions on the brain were seen. Vitamin K (Vit. K), is the effective treatment for the curing of bromadiolone, was identified.</p> Conclusions <p>This review suggests that in the case of bromadiolone poisoning, it is very important to find out the poisoned compound and not to rely only on symptomatic treatment. It is found that Vit. K is the major curative treatment for the survival of bromadiolone poisoning victims.</p>