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<p>The field of regenerative medicine has witnessed significant advancements in recent years, particularly in the application of biomaterials to enhance stem cell differentiation. Biomaterials serve as scaffolds that can support cellular functions and influence the fate of stem cells through biochemical and physical cues. This paper reviews recent advancements in biomaterials designed for stem cell differentiation, focusing on their composition, properties, and applications in tissue engineering. We explore various types of biomaterials, including natural polymers, synthetic polymers, hydrogels, and nanomaterials, and discuss how they can be tailored to create microenvironments that promote specific differentiation pathways. Additionally, we highlight the challenges and future directions in this rapidly evolving field.</p> Graphical Abstract <p></p>

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Advancements in Biomaterials for Stem Cell Differentiation

  • 期刊论文

  • 发表日期：

    2025年4月21日

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  • Mingchen Shao,
  • Mohamad Rahmdel,
  • Sepideh Karkon Shayan,
  • Elham Hassannia,
  • Mohammad khedmatgozar,
  • Khadije Yousefi,
  • Payam Ali-khiavi,
  • Ahmed Hjazi,
  • Raed Fanoukh Aboqader Al-Aouadi,
  • Paria Arjmandi Sarvestani,
  • Mohammad Reza Ghasemzadeh Fard,
  • Mehrdad Nourizadeh,
  • Saeid Shabestari Khiabani,
  • Muath Suliman,
  • Paria Ganji Nataj,
  • Sina hamzehzadeh

摘要

The field of regenerative medicine has witnessed significant advancements in recent years, particularly in the application of biomaterials to enhance stem cell differentiation. Biomaterials serve as scaffolds that can support cellular functions and influence the fate of stem cells through biochemical and physical cues. This paper reviews recent advancements in biomaterials designed for stem cell differentiation, focusing on their composition, properties, and applications in tissue engineering. We explore various types of biomaterials, including natural polymers, synthetic polymers, hydrogels, and nanomaterials, and discuss how they can be tailored to create microenvironments that promote specific differentiation pathways. Additionally, we highlight the challenges and future directions in this rapidly evolving field.

Graphical Abstract