Scholarlink

<p>Soybean (<i>Glycine max</i> (L.) Merr.) is considered a key global food source, valued for their bioactive isoflavones, which exhibit antioxidant, anti-inflammatory, and phytoestrogenic properties. However, conventional solvent-based extractions face challenges such as low selectivity, inefficient recovery of glycosylated isoflavones, and environmental concerns. This study developed a green, efficient extraction method using Natural Deep Eutectic Solvent (NADES)-based ultrasound-assisted extraction (UAE). A choline chloride-ascorbic acid (1:1) NADES system yielded 795.8&#xa0;µg/g DW isoflavones, outperforming conventional 50% ethanol extraction (723.5&#xa0;µg/g DW). Optimization using Box-Behnken Design identified 39% water content, 55 °C, and 64 min as ideal conditions, with water content and temperature being key factors. These optimized NADES conditions resulted in isoflavone extraction yield of (1076.78 µg/g DW). COSMO-RS computational modeling revealed NADES-isoflavone interactions, emphasizing hydrogen bonding and polarity. This eco-friendly method enhances efficiency, reduces environmental impact, and supports NADES as a sustainable alternative for bioactive phytochemical extraction.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Green and Efficient Extraction of Soybean (Glycine max (L.) Merr.) Isoflavones Using Natural Deep Eutectic Solvents-Based Ultrasound-Assisted Extraction

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月15日

查看全文
  • Rahma SR. Mahrous,
  • Basem Abdel Fattah,
  • Yousef Abdel Rahman,
  • Shaimaa M. Sallam,
  • Eman Shawky

摘要

Soybean (Glycine max (L.) Merr.) is considered a key global food source, valued for their bioactive isoflavones, which exhibit antioxidant, anti-inflammatory, and phytoestrogenic properties. However, conventional solvent-based extractions face challenges such as low selectivity, inefficient recovery of glycosylated isoflavones, and environmental concerns. This study developed a green, efficient extraction method using Natural Deep Eutectic Solvent (NADES)-based ultrasound-assisted extraction (UAE). A choline chloride-ascorbic acid (1:1) NADES system yielded 795.8 µg/g DW isoflavones, outperforming conventional 50% ethanol extraction (723.5 µg/g DW). Optimization using Box-Behnken Design identified 39% water content, 55 °C, and 64 min as ideal conditions, with water content and temperature being key factors. These optimized NADES conditions resulted in isoflavone extraction yield of (1076.78 µg/g DW). COSMO-RS computational modeling revealed NADES-isoflavone interactions, emphasizing hydrogen bonding and polarity. This eco-friendly method enhances efficiency, reduces environmental impact, and supports NADES as a sustainable alternative for bioactive phytochemical extraction.