Scholarlink

<p>The brewing industry generates significant waste, including spent hops—a rich source of flavonoids, particularly xanthohumol (XN), known for its antimicrobial, anticancer, antiaging, and anti-inflammatory properties. This study examines how solvent polarity affects the extraction of total phenolic compounds, flavonoids, and XN from hops after industrial-scale supercritical CO₂ extraction. Various water-isopropanol and water–ethanol ratios were tested, with polarity indexes calculated. Results showed that solvent polarity significantly impacts extraction yields. The optimal polarity index for XN and flavonoid extraction is 6–7, while for phenolic compounds, it ranges from 6 to 9. Adding water (about 50% vol.) increased XN yield by up to 85% compared to pure organic solvents while reducing chemical use. Given that XN constitutes 0.2–1.1% w/w of dry hops, yields of up to 0.085% w/w are considerable. Due to ethanol’s cost, isopropanol-water (50:50 v/v) is recommended. Samples obtained with 50% alcohol also showed the highest antioxidant activity according to the Ferric-Ion Reducing Antioxidant Power (FRAP) methodology. FT-IR analysis revealed that water-organic solvent mixtures extracted higher amounts of lipids, fatty acids, esters and waxes than pure solvents. Given XN’s applications in pharmacy and cosmetology, future research should focus on purifying extracts and/or pretreating raw materials before extraction.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Extraction of Valuable Compounds from Spent Hops, Including Xanthohumol—The Influence of the Solvent’s Polarity Index

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月29日

查看全文
  • Aleksandra Modzelewska,
  • Mateusz Jackowski,
  • Anna Trusek

摘要

The brewing industry generates significant waste, including spent hops—a rich source of flavonoids, particularly xanthohumol (XN), known for its antimicrobial, anticancer, antiaging, and anti-inflammatory properties. This study examines how solvent polarity affects the extraction of total phenolic compounds, flavonoids, and XN from hops after industrial-scale supercritical CO₂ extraction. Various water-isopropanol and water–ethanol ratios were tested, with polarity indexes calculated. Results showed that solvent polarity significantly impacts extraction yields. The optimal polarity index for XN and flavonoid extraction is 6–7, while for phenolic compounds, it ranges from 6 to 9. Adding water (about 50% vol.) increased XN yield by up to 85% compared to pure organic solvents while reducing chemical use. Given that XN constitutes 0.2–1.1% w/w of dry hops, yields of up to 0.085% w/w are considerable. Due to ethanol’s cost, isopropanol-water (50:50 v/v) is recommended. Samples obtained with 50% alcohol also showed the highest antioxidant activity according to the Ferric-Ion Reducing Antioxidant Power (FRAP) methodology. FT-IR analysis revealed that water-organic solvent mixtures extracted higher amounts of lipids, fatty acids, esters and waxes than pure solvents. Given XN’s applications in pharmacy and cosmetology, future research should focus on purifying extracts and/or pretreating raw materials before extraction.