Scholarlink

<p>The search for new natural bioactive compounds has recently been intensified; however, some compounds are unstable under atmospheric conditions, suffering degradation and loss of bioactivity. Encapsulation is a strategy employed in the food industry to enhance the stability of such labile compounds. This study presents a novel microencapsulation method for preserving terpene-rich extracts from the microalga <i>Dunaliella salina</i> with potential neuroprotective activity. Microliposomes were formed using phosphatidylcholine as encapsulating agent, creating a nanoemulsion stabilized by lyophilization. A purification step yielded a pure encapsulated product with an efficiency of 63%. The behavior of key compounds, particularly terpenes and carotenoids, was analyzed throughout the encapsulation process. Low molecular weight terpenes were the most affected by processing temperatures, while carotenoid encapsulation was linked to their structure-concentration relationship. Stability tests under accelerated storage conditions (45&#xa0;°C) revealed only a 20% reduction in bioactivity over three months, demonstrating high stability under extreme conditions.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Improving the Long-Term Stability of Carotenoids from Dunaliella Salina Supercritical Fluid Extracts with a New Liposomal Encapsulation Based on Cryogenic and Stirring Processes

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月21日

查看全文
  • Victor M. Amador-Luna,
  • Miguel Herrero,
  • Pablo Mendoza-Orbaneja,
  • Elena Ibáñez,
  • Lidia Montero

摘要

The search for new natural bioactive compounds has recently been intensified; however, some compounds are unstable under atmospheric conditions, suffering degradation and loss of bioactivity. Encapsulation is a strategy employed in the food industry to enhance the stability of such labile compounds. This study presents a novel microencapsulation method for preserving terpene-rich extracts from the microalga Dunaliella salina with potential neuroprotective activity. Microliposomes were formed using phosphatidylcholine as encapsulating agent, creating a nanoemulsion stabilized by lyophilization. A purification step yielded a pure encapsulated product with an efficiency of 63%. The behavior of key compounds, particularly terpenes and carotenoids, was analyzed throughout the encapsulation process. Low molecular weight terpenes were the most affected by processing temperatures, while carotenoid encapsulation was linked to their structure-concentration relationship. Stability tests under accelerated storage conditions (45 °C) revealed only a 20% reduction in bioactivity over three months, demonstrating high stability under extreme conditions.