Outcomes of Endoscopic Dilation for Radiation Therapy-Related Esophageal Stricture
摘要
Esophageal dilation is commonly used to improve swallowing function and nutritional status in cancer patients with radiation-induced esophageal strictures. However, radiation-induced strictures are among the most refractory to dilation. Understanding the success and limitations of this procedure is crucial for optimizing cancer patient outcomes.
Recent FindingsThe overall success rate for dilation of benign esophageal strictures has been reported as ranging from 66 to 84%. However, radiation-induced esophageal strictures are more often complex and among the most refractory to dilation.
SummaryThis is the largest known single study of esophageal dilation for radiation-induced strictures. Dilation was associated with weight gain in 47.2% of patients, gastrostomy tube removal in 3.3%, both forms of improvement in 9.4%, and no change in 40.0% though 18.3% of patients required 8 or more dilations. None of the studied stricture and dilation parameters appeared to affect the success rate. There was no difference in clinical outcome when either Savary or balloon dilation were used; however, it was more likely both tools would be used as the number of dilations increased.