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Purpose of Review <p>This narrative review aims to discuss the latest evidence for cell-free tumor DNA (ctDNA) use in bladder cancer, future perspectives and challenges in implementing this technology in clinical practice.</p> Recent Findings <p>Recent papers describe promising findings regarding ctDNA analysis in blood samples and in urine of bladder cancer patients. This biomarker can be used as a diagnostic tool, in prognostic evaluation and as additional data for treatment indication and surveillance.</p>

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Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder

  • 期刊论文

  • 发表日期：

    2025年2月12日

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  • Lucas Motta Martinez,
  • Lorena Cristina São Leão Ribeiro,
  • Rodrigo Gilles Guidi,
  • Caio Mazzonetto Teofilo de Moraes,
  • Catharina Ribeiro Lyra,
  • Bruno Liebl,
  • Vinicius Henrique Almeida Guimarães,
  • Richard Dobrucki de Lima,
  • Lucas Schenk de Almeida,
  • Caio Vinicius Suartz,
  • William Carlos Nahas,
  • Leopoldo Alves Ribeiro-Filho

摘要

Purpose of Review

This narrative review aims to discuss the latest evidence for cell-free tumor DNA (ctDNA) use in bladder cancer, future perspectives and challenges in implementing this technology in clinical practice.

Recent Findings

Recent papers describe promising findings regarding ctDNA analysis in blood samples and in urine of bladder cancer patients. This biomarker can be used as a diagnostic tool, in prognostic evaluation and as additional data for treatment indication and surveillance.