Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status

期刊论文
发表日期：

2024年4月16日

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Toshihiro Iguchi,
Yusuke Matsui,
Koji Tomita,
Mayu Uka,
Noriyuki Umakoshi,
Takahiro Kawabata,
Hideo Gobara,
Motoo Araki,
Takao Hiraki

摘要

Purpose of review

To review the current status of kidney tumor ablation in patients with substantial kidney impairment.

Recent findings

Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD.

Summary

According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.