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Purpose of Review <p>The COVID-19 pandemic had a profound global impact with extensive implications for solid organ transplantation. This review summarizes key lessons learned by the transplant community and highlights their relevance for preparedness in future outbreaks.</p> Recent Findings <p>Studies examining the impact of COVID-19 and solid organ transplantation have centered on clinical epidemiology, outcomes in solid organ transplant recipients, the role of vaccines in prevention, peri-transplant management, and application for future outbreaks.</p> Summary <p>The pandemic caused high mortality and reduced transplant volume but also yielded important lessons. Transplant recipients experienced higher rates of hospitalization, mortality, and ICU admissions, with only modest benefit from antivirals. Reduced vaccine efficacy underscored the need for improved preventive strategies. Observational data guided use of SARS-CoV-2–positive donors and recipients peri-transplant. These experiences highlight the importance of robust international networks for research and knowledge sharing to strengthen transplant care and preparedness for future outbreaks.</p>

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COVID-19 and Solid Organ Transplantation: What We Learned and Where We are Going

  • 期刊论文

  • 发表日期：

    2026年4月1日

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  • Jonathan Huang,
  • Stephanie Pouch

摘要

Purpose of Review

The COVID-19 pandemic had a profound global impact with extensive implications for solid organ transplantation. This review summarizes key lessons learned by the transplant community and highlights their relevance for preparedness in future outbreaks.

Recent Findings

Studies examining the impact of COVID-19 and solid organ transplantation have centered on clinical epidemiology, outcomes in solid organ transplant recipients, the role of vaccines in prevention, peri-transplant management, and application for future outbreaks.

Summary

The pandemic caused high mortality and reduced transplant volume but also yielded important lessons. Transplant recipients experienced higher rates of hospitalization, mortality, and ICU admissions, with only modest benefit from antivirals. Reduced vaccine efficacy underscored the need for improved preventive strategies. Observational data guided use of SARS-CoV-2–positive donors and recipients peri-transplant. These experiences highlight the importance of robust international networks for research and knowledge sharing to strengthen transplant care and preparedness for future outbreaks.