Purpose of Review <p>We examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational and implementation science.</p> Recent Findings <p>The peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings.</p> Summary <p>This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.</p>

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Envisioning a Multidisciplinary HBV Cure Research Agenda

  • Karine Dubé,
  • Ali Ahmed,
  • Chari Cohen,
  • Yasmin Ibrahim,
  • George A. Yendewa,
  • Edward R. Cachay,
  • Su Wang,
  • Kristen Marks,
  • Arthur Y. Kim,
  • Jeremy Sugarman,
  • David L. Thomas,
  • Chloe L. Thio,
  • Debika Bhattacharya

摘要

Purpose of Review

We examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational and implementation science.

Recent Findings

The peer-reviewed literature on the multi-disciplinary aspects of HBV cure research is gradually expanding, although several areas still require attention. These deficiencies include: the acceptability of HBV treatment discontinuations, HBV-related stigma, the impact of co-infections (e.g., HIV), and the translation of discoveries to resource-limited settings.

Summary

This review highlights the importance of a multidisciplinary framework that bridges socio-behavioral sciences, ethics, community engagement, and translational and implementation science to help ensure the development of an effective, acceptable, scalable and equitable HBV cure.