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Purpose of Review <p>The objective of this review is to highlight contemporary data describing frequency and mechanisms of racial and ethnic disparities along the continuum of care for hepatocellular carcinoma (HCC).</p> Recent Findings <p>Epidemiologic data shows that negative outcomes including more late stage cancer at diagnosis, lower treatment utilization, and worse survival are still being observed among Hispanic and Black patients with HCC. In general, Asians have better outcomes though this is not uniform across all Asian ethnicities. A few key contributors to these disparities include genetic ancestry, social determinants of health such as nativity, poverty, and insurance, and structural racism.</p> Summary <p>Continual assessments of racial and ethnic differences in HCC presentation and outcomes are needed as gaps have persisted. Building of more granular and prospective clinical cohorts will shed greater light on potential mechanisms and provide actionable targets for effective multilevel interventions.</p>

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Racial and Ethnic Disparities among Patients with Hepatocellular Carcinoma: A Review of Contemporary Literature

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月24日

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  • Ariel Lee,
  • Phillip Chung,
  • Kali Zhou

摘要

Purpose of Review

The objective of this review is to highlight contemporary data describing frequency and mechanisms of racial and ethnic disparities along the continuum of care for hepatocellular carcinoma (HCC).

Recent Findings

Epidemiologic data shows that negative outcomes including more late stage cancer at diagnosis, lower treatment utilization, and worse survival are still being observed among Hispanic and Black patients with HCC. In general, Asians have better outcomes though this is not uniform across all Asian ethnicities. A few key contributors to these disparities include genetic ancestry, social determinants of health such as nativity, poverty, and insurance, and structural racism.

Summary

Continual assessments of racial and ethnic differences in HCC presentation and outcomes are needed as gaps have persisted. Building of more granular and prospective clinical cohorts will shed greater light on potential mechanisms and provide actionable targets for effective multilevel interventions.