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Purpose of review <p>In this brief review we discuss definition of portal hypertension, how to measure it through hepatic venous pressure gradient as well as its main clinical use. </p> Recent findings <p>With the expanding role of non-invasive methods to diagnose and monitor portal hypertension, the role of HVPG measurement has significantly changed. However, there are still significant clinical and research roles that can only be achieved by invasive HVPG measurements. </p> Summary <p>HVPG measurement is crucial in assessing and developing pharmacological therapies, in addition to its role in clinical practice. However, it has its limitations including availability and invasiveness. Future studies should focus on finding modalities that can be as accurate as HVPG but non-invasive.</p>

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Hepatic Venous Pressure Gradient Measurement and its Limitation

  • 期刊论文

  • 发表日期：

    2025年2月25日

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  • Nadera Altork,
  • Spyridon Peppas,
  • Atoosa Rabiee

摘要

Purpose of review

In this brief review we discuss definition of portal hypertension, how to measure it through hepatic venous pressure gradient as well as its main clinical use.

Recent findings

With the expanding role of non-invasive methods to diagnose and monitor portal hypertension, the role of HVPG measurement has significantly changed. However, there are still significant clinical and research roles that can only be achieved by invasive HVPG measurements.

Summary

HVPG measurement is crucial in assessing and developing pharmacological therapies, in addition to its role in clinical practice. However, it has its limitations including availability and invasiveness. Future studies should focus on finding modalities that can be as accurate as HVPG but non-invasive.