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Troponin Elevation in Asymptomatic Cancer Patients: Unveiling Connections and Clinical Implications

  • Sebastian W Romann,
  • Evangelos Giannitsis,
  • Norbert Frey,
  • Lorenz H. Lehmann

摘要

Purpose of the review

Elevated troponin levels are well established e.g., for the diagnosis of suspected acute coronary syndrome in symptomatic patients. In contrast, troponin elevations in asymptomatic cancer patients emerge as a complex phenomenon, challenging traditional perceptions of its association solely with cardiac events.

Recent findings

Recent data support the predictive value of cardiac biomarker for all-cause mortality and cardiotoxicity in cancer patients. This review gives an overview about the current literature about cardiac troponins in prediction and identification of high-risk cancer patients. The overview is focusing on diagnostic challenges, biomarker significance, and gaps of knowledge.

Summary

Latest publications highlight the relevance of cardiac troponin in risk analysis before cancer treatment as well as a potential diagnostic gatekeeper for further cardiological diagnostics and therapy.