Purpose of Review <p>We present an introduction to the neuroimmune axis with a focus on the gastrointestinal system, its role in numerous chronic multisystem disorders, and emerging tools and therapies to diagnose and treat these conditions.</p> Recent Findings <p>There have recently been tremendous breakthroughs in our understanding of how the nervous, immune, and endocrine systems, as well as the extracellular matrix and microbiota, interact within the gastrointestinal system to modulate health and disease.</p>

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The Neuroimmune Axis in Gastrointestinal Disorders – An Underrecognized Problem

  • Laura A. Pace,
  • Niwen Kong,
  • Mohamed I. Itani,
  • James Hemp

摘要

Purpose of Review

We present an introduction to the neuroimmune axis with a focus on the gastrointestinal system, its role in numerous chronic multisystem disorders, and emerging tools and therapies to diagnose and treat these conditions.

Recent Findings

There have recently been tremendous breakthroughs in our understanding of how the nervous, immune, and endocrine systems, as well as the extracellular matrix and microbiota, interact within the gastrointestinal system to modulate health and disease.