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Purpose of Review <p>To review studies evaluating the first presentation of atherosclerotic cardiovascular disease in previously asymptomatic individuals.</p> Recent Findings <p>Prior studies have evaluated the first presentation of a broad range of CVD events. In a recent study from the Multi-Ethnic Study of Atherosclerosis, ASCVD events were evaluated specifically in a population of previously asymptomatic individuals. Death/resuscitated cardiac arrest was the most common first presentation, and this disproportionately affected women and Black individuals. CAC scoring was identified as a potential tool to identify individuals at risk.</p> Summary <p>The first presentation of ASCVD is often severe, including death. This emphasizes the need for risk assessment and preventive therapies in appropriate individuals.</p>

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First Presentation of Atherosclerotic Cardiovascular Disease in Previously Healthy Individuals

  • 期刊论文

  • 发表日期：

    2026年3月21日

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  • Jonathan Kermanshahchi,
  • Harpreet S. Bhatia

摘要

Purpose of Review

To review studies evaluating the first presentation of atherosclerotic cardiovascular disease in previously asymptomatic individuals.

Recent Findings

Prior studies have evaluated the first presentation of a broad range of CVD events. In a recent study from the Multi-Ethnic Study of Atherosclerosis, ASCVD events were evaluated specifically in a population of previously asymptomatic individuals. Death/resuscitated cardiac arrest was the most common first presentation, and this disproportionately affected women and Black individuals. CAC scoring was identified as a potential tool to identify individuals at risk.

Summary

The first presentation of ASCVD is often severe, including death. This emphasizes the need for risk assessment and preventive therapies in appropriate individuals.