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Purpose of Review <p>To provide a comprehensive review of cardiovascular risks associated with premature menopause.</p> Recent Findings <p>Premature menopause, defined as permanent cessation of menstruation before the age of 40, is associated with an increased risk of developing cardiovascular disease. A variety of disease states and treatment exposures can lead to premature menopause resulting in a growing population of women at risk for the development of cardiovascular disease. This review summarizes current data substantiating the adverse cardiovascular outcomes seen in premature ovarian insufficiency, surgical menopause, polycystic ovarian syndrome, and cancer treatment-induced menopause.</p> Summary <p>Premature menopause significantly increases the risk of long-term cardiovascular events. Multidisciplinary healthcare models that emphasize screening women with premature menopause for cardiovascular risk factors are essential to improving the cardiovascular health and longevity of this vulnerable population.</p>

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Cardiovascular Consequences of Premature Menopause

  • 期刊论文

  • 发表日期：

    2025年8月13日

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  • Julia A. Bast,
  • Olubunkola Olubi,
  • D. Elizabeth Le,
  • Susmita Parashar,
  • Ioana Dobrescu,
  • Lavanya Kondapalli

摘要

Purpose of Review

To provide a comprehensive review of cardiovascular risks associated with premature menopause.

Recent Findings

Premature menopause, defined as permanent cessation of menstruation before the age of 40, is associated with an increased risk of developing cardiovascular disease. A variety of disease states and treatment exposures can lead to premature menopause resulting in a growing population of women at risk for the development of cardiovascular disease. This review summarizes current data substantiating the adverse cardiovascular outcomes seen in premature ovarian insufficiency, surgical menopause, polycystic ovarian syndrome, and cancer treatment-induced menopause.

Summary

Premature menopause significantly increases the risk of long-term cardiovascular events. Multidisciplinary healthcare models that emphasize screening women with premature menopause for cardiovascular risk factors are essential to improving the cardiovascular health and longevity of this vulnerable population.