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Purpose of Review <p>To provide an overview of the diagnosis and updated therapeutic approach to autoimmune pericarditis.</p> Recent Findings <p>Subtypes of autoimmune pericarditis may benefit from IL-1 inhibition and future phenotyping based on clinical presentation, biomarkers, and imaging may aid in guiding future therapeutic approaches.</p> Summary <p>Autoimmune pericarditis is a unique phenotype of pericarditis for which there is scarce data. The clinical spectrum of pericardial involvement associated with autoimmune disorders varies in acuity, recurrence, severity, and symptomatic presentation. There is a pathophysiologic distinction that separates autoimmune and autoinflammatory pericarditis from other pericarditis presentations. This review explores the state of the art in diagnosis and therapeutic management.</p>

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Autoimmune Pericarditis: Diagnosis and New Therapeutics

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月15日

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  • Heba Wassif,
  • Elizabeth Ghandakly,
  • Habib Layoun,
  • Jaideep Singh Bhalla,
  • Emily Littlejohn,
  • Tom Kai Ming Wang,
  • Elaine Husni,
  • Allan Klein

摘要

Purpose of Review

To provide an overview of the diagnosis and updated therapeutic approach to autoimmune pericarditis.

Recent Findings

Subtypes of autoimmune pericarditis may benefit from IL-1 inhibition and future phenotyping based on clinical presentation, biomarkers, and imaging may aid in guiding future therapeutic approaches.

Summary

Autoimmune pericarditis is a unique phenotype of pericarditis for which there is scarce data. The clinical spectrum of pericardial involvement associated with autoimmune disorders varies in acuity, recurrence, severity, and symptomatic presentation. There is a pathophysiologic distinction that separates autoimmune and autoinflammatory pericarditis from other pericarditis presentations. This review explores the state of the art in diagnosis and therapeutic management.