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Going from Primary to Primordial Prevention: Is the Juice Worth the Squeeze?

  • Andrew Chiou,
  • Melody Hermel,
  • Zohar Chai,
  • Ariana Eiseman,
  • Sheila Jeschke,
  • Sandeep Mehta,
  • Unab Khan,
  • Zahra Hoodbhoy,
  • Nilofer Safdar,
  • Adeel Khoja,
  • Vashma Junaid,
  • Elizabeth Vaughan,
  • Anwar T. Merchant,
  • Junaid Iqbal,
  • Aysha Almas,
  • Salim S. Virani,
  • Sana Sheikh

摘要

Purpose of Review

While primary prevention strategies target individuals who are at high risk of cardiovascular disease, there is rising interest towards primordial prevention that focuses on preventing the development of risk factors upstream of disease detection. Therefore, we review the advantages of primordial prevention interventions on minimizing future cardiovascular events.

Recent Findings

Primordial prevention of atherosclerotic cardiovascular disease involves behavioral, genetic, and environmental strategies, starting from fetal/infant health and continuing throughout childhood and young adulthood. Early interventions focusing on modifiable risk factors such as physical inactivity, non-ideal body weight, smoking, and environmental pollutants are important towards preventing the initial occurrence of risk factors such as hypertension, dyslipidemia, and diabetes to ultimately reduce cardiovascular disease.

Summary

Implementing primordial prevention strategies early on in life can minimize cardiovascular events and lead to healthy aging in the population. Future studies can further evaluate the effectiveness of various primordial prevention strategies.