Purpose of Review <p>We appraise recent clinical trials, cohort studies, and meta-analyses on dietary and physical activity interventions for prevention and management of high blood pressure.</p> Recent Findings <p>We identified several notable new findings. Using a new statistical model for estimation of treatment dose-response patterns, potassium supplementation demonstrated a U-curve relationship, in contrast to the linear association for other exposures studied. Recent salt substitute reports document substantial BP lowering and prevention of cardiovascular and all-cause mortality. A large and statistically powerful alcohol dose-response meta-analysis of prospective cohort studies suggests there is no beneficial or safe level for alcohol consumption. Finally, large meta-analyses suggest isometric resistance exercise has substantial capacity to lower BP. A major area of uncertainty remains how best to implement the desired dietary and physical activity interventions.</p> Summary <p>In addition to confirming and expanding core knowledge for the role of diet and physical activity in the etiology, prevention and management of high blood pressure, reports during the last 5 years have added to our understanding of dose-response relationships for sodium, potassium, physical activity, and alcohol consumption with high blood pressure, have detailed the efficacy of new treatment options, and have ighlighted areas of continuing uncertainty.</p>