Background <p>Sleep is the most effective state to reset brain activity and is crucial for overall health. Medical college students are among the most vulnerable groups at risk of experiencing poor sleep quality, which can lead to suboptimal academic performance.</p> Aim and Objectives <p> This study aimed to assess the sleep quality and daytime sleepiness of medical students. The objective of the study was to determine the correlation between academic performance and their characteristics.</p> Materials and Methods <p>The study is institution-based, cross-sectional, and noninterventional. A total of 183 medical students were recruited from four professional years. The sleep quality, daytime sleepiness, and perceived academic performance were collected using a structured questionnaire. Pittsburgh Sleep Quality Scale and Epworth Sleepiness Scale were used. Among other questions were the causes of sleep disturbances and the perceived academic performance, which was self-reported.</p> Results <p> 38.3% of students reported excessive daytime sleepiness (ESS &gt; 10), and 80.9% had poor sleep quality. A negative correlation was found between daytime sleepiness (r=-0.768, p=0.000) and perceived academic performance and between sleep quality and academic performance. (r = -0.337, p=0.000).</p> Conclusion <p> This study underscores the need for strategies to improve sleep quality among medical students to enhance their academic performance and well-being<i>.</i></p>